Orodispersible tablets are novel oral drug-delivery system as they have improved patient compliance and for those patients having difficulty in swallowing tablet. They have a medicinal substance which rapidly disintegrates within second when placed on tongue. Metoclopramide hydrochloride tablet is prepared by using superdisintegrants crospovidone and croscarmellose sodium by direct compression technique. The hardness of all the formulations was found in the range of 6.51�±0.21 kg/cm2. The friability of formulation F1-F6 was found to be in the range of 0.20-0.15 which was within the IP limit i.e below 1%. The drug content of all the formulation was found in the range of 98.85-99.25 % which was whithin acceptable limit. The In-vitro disintegration time of all formulation was found in the range of 18-12 sec. Wetting time which is the important parameter for understanding the capacity of disintegrants to swell in presence of little amount of water were found to be in the range of 23-20 sec. All the formulations releases the drug within 5-10 minutes.
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